The RECOVERY trial is a large, ongoing, multi-centre, open-label, randomized controlled trial investigating several treatments for patients hospitalized with COVID-19. In July 2020, the preliminary results were published comparing dexamethasone plus usual standard of care with usual standard of care alone. Dexamethasone reduced the 28-day mortality rate in patients hospitalized with COVID-19. The purpose of this CADTH report is to describe the internal and external validity of these published results of the RECOVERY trial.
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