This report reviews the current scientific evidence on the potential benefits and harms of chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19. A total of four trials were identified — three treatment trials and one prevention trial. The evidence available at this time is limited in both quantity and quality, with some of the studies terminated early due to safety concerns. However, CADTH will continue to update this report as more evidence becomes available.

Link to Report

Chloroquine or Hydroxychloroquine to Prevent or Treat COVID-19

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