Ventilation and Perfusion Imaging for the Diagnosis of Pulmonary Embolisms During the COVID-19 Pandemic: A Review of Safety and Guidelines

This Rapid Response review looked for clinical evidence and evidence-based guidelines on ventilation-perfusion imaging for diagnosing pulmonary embolism during the COVID-19 pandemic. Because the procedure often induces coughing in patients, there are concerns about its potential role in transmitting COVID-19 infection from patients to health care providers. However, no relevant evidence or evidence-based guidelines were […]

Wearable Devices for Monitoring and Detecting COVID-19 Symptoms

Wearable devices — such as watches, arm bands, and patches — may help reduce the spread of COVID-19. Wearable technologies could improve early symptom detection, especially through close monitoring of contacts . They may also safely monitor patients from a distance and limit health care worker exposure. This bulletin explores different wearable technologies in the […]

Testing for COVID-19 in Correctional Facilities: Clinical Effectiveness and Guidelines

CADTH conducted a Rapid Response report to search for evidence on the clinical effectiveness of COVID-19 testing for all new admissions to correctional facilities, as well as the clinical effectiveness of mass testing (i.e., testing everyone within the correctional facility for COVID-19). CADTH also searched for any evidence-based guidelines on these topics. However, no relevant […]

Contact Tracing for Potential Exposure to SARS-CoV-2 Virus: Guidelines

CADTH conducted a Rapid Response search for evidence-based guidelines regarding contact tracing for people who have been in contact with a person with a suspected or confirmed diagnosis of the coronavirus disease (COVID-19). No relevant evidence-based guidelines were identified; therefore, no conclusions can be drawn. Note that a list of potentially relevant citations can be […]

Portable or Temporary Negative Pressure Rooms for Tuberculosis: Clinical Effectiveness and Guidelines

This Rapid Response review aimed to identify available evidence on the clinical effectiveness of portable or temporary negative pressure rooms and related evidence-based guidelines for the management of people with active tuberculosis. The review included a search for relevant studies on COVID-19 and other respiratory illnesses. As no relevant studies or guidelines on this topic […]

Infection Prevention and Control Measures in Mental Health Facilities: Guidelines

CADTH conducted a Rapid Response search for evidence-based guidelines regarding infection prevention or control measures in mental health treatment facilities. No relevant evidence-based guidelines were identified; therefore, no conclusions can be drawn based on this review. Note that a list of other potentially relevant citations can be found in the report’s Appendix. Link to Report […]

Pre-Treatment Mouth Rinses for Dental Patients With Suspected SARS or COVID-19: Clinical Effectiveness and Guideline

No literature was identified regarding the clinical effectiveness of pre-dental treatment mouth rinses for patients with suspected severe acute respiratory syndrome or coronavirus disease. Additionally, no evidence-based guidelines were identified regarding the use of pre-dental treatment mouth rinses in patients with suspected severe acute respiratory syndrome or coronavirus disease. Link to Report Pre-Treatment Mouth Rinses […]

SARS-CoV-2 Longevity on and Transmission via Materials: Evidence

One non-randomized study was identified regarding the lifespan of severe acute respiratory syndrome coronavirus 2 on different materials. No clinical evidence was identified regarding severe acute respiratory syndrome coronavirus 2 transmission via materials. Link to Report SARS-CoV-2 Longevity on and Transmission via Materials: Evidence

SARS-CoV-2 Longevity on and Transmission via Materials: Evidence

This report reviewed the available literature on the lifespan of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on different materials, as well as its potential for transmission via these materials. One non-randomized study was identified, which reported that SARS-CoV-2 was viable on plastic and stainless steel for up to 72 hours, on copper for up […]

Hand Washing for Health Care Workers to Reduce the Transmission of Infection: Clinical Effectiveness and Guidelines

In response to the COVID-19 pandemic, CADTH looked for studies on hand washing for health care workers to reduce the transmission of infection. One systematic review and one non-randomized study were identified regarding the clinical effectiveness of hand washing with soap and water compared with hand sanitization solutions. Three evidence-based guidelines were identified regarding the […]

Masks During Aerosol-Generating Dental Procedures: Clinical Effectiveness and Guidelines

In response to the COVID-19 pandemic, CADTH looked for studies on the effectiveness of masks to protect dental clinicians from acquired infections during aerosol-generating dental procedures. One non-randomized study on the clinical effectiveness of masks was identified. No relevant evidence-based guidelines on this topic were found. Note, however, that all masks for medical use must […]

Non-Manual Room Disinfection Techniques for Infection Prevention in Health Care Facilities: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

This report summarizes the abstracts of studies on non-manual room disinfection methods for preventing hospital-acquired infections. It might be of interest to those making decisions on how to disinfect rooms where COVID-19 patients have been treated. The included studies investigated products and devices that use ultraviolet light, hydrogen peroxide vapour, and copper for room disinfection. […]

New Disinfection Technologies to Reduce Health Care-Associated Infections

This bulletin (2017) reviewed five environmental disinfection measures that may supplement standard cleaning and disinfection strategies: blue-violet light disinfection for hospital rooms, a pulsed-xenon UV light disinfection system for hospital rooms, a countertop UV-C light disinfection system for mobile devices, antimicrobial compressed salt for high-touch surfaces, and shark skin-like micropatterned surfaces to reduce bacterial adhesion. […]

Antimicrobial Copper Surfaces for the Reduction of Health Care–Associated Infections in Intensive Care Settings

This report evaluated the evidence for the installation of antimicrobial copper surfaces as an infection control mechanism in health care settings. Limited evidence was found at the time of publication (2015); confirmation of a sustained reduction in infection rates over time and the cost-effectiveness of replacing existing surfaces with antimicrobial copper surfaces in Canadian health […]

Aerosol-Generating Procedures and Risk of Transmission of Acute Respiratory Infections: A Systematic Review

The COVID-19 pandemic puts health care workers treating COVID-19 patients at risk of becoming infected themselves. CADTH previously conducted a systematic review to evaluate the evidence for the risk of transmission of acute respiratory infections to health care workers caring for patients undergoing aerosol-generating procedures. Very low-quality evidence suggested that some aerosol-generating procedures were associated […]

Physical Interventions to Interrupt or Reduce the Spread of Respiratory Viruses — Resource Use Implications: A Systematic Review

CADTH previously conducted a systematic review to evaluate resource use and economic considerations related to physical interventions aimed at interrupting or reducing the spread of respiratory viruses. Such interventions include screening at points of entry, isolation, quarantine, social distancing, barriers, personal protection (e.g., wearing masks, gloves, and gowns), and hand hygiene. This report may be […]