Ongoing Trials of Plasma-Based Therapies for the Treatment of COVID-19

This report provides information on ongoing randomized controlled trials of intravenous immune globulin and hyperimmune globulin that are being investigated for the management of COVID-19. It will be updated every month. Ongoing trials of convalescent plasma are addressed in separate CADTH reports Link to Report Ongoing Trials of Plasma-Based Therapies for the Treatment of COVID-19 […]

Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19

This report provides information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19. It will be updated every two weeks. Ongoing trials of vaccines and plasma-based therapies are addressed in separate CADTH reports. Link to Report Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19 (Updated November 20, […]

Synopsis of Reference Search Results for Topics in Long-Term Care

The COVID-19 pandemic has been challenging for those living and working in long-term care (LTC) facilities. There has been uncertainty related to managing visitors to LTC, the psychological and social impact of isolation for LTC residents, and how best to support LTC staff during this pandemic. To help support health care decision-makers facing these issues, […]

Remdesivir: Evidence Review and Appraisal

CADTH conducted a Health Technology Review on remdesivir — an antiviral drug currently being used to treat COVID-19. Remdesivir was approved in Canada on July 27, 2020 to treat adults and adolescents with severe symptoms of COVID-19 who have pneumonia and require extra oxygen. Four randomized controlled trials were identified and included in the review. […]

Protective Eyewear for Health Care Workers: Clinical Effectiveness and Guidelines

This CADTH Rapid Response Report looks at evidence and recommendations regarding the clinical effectiveness of protective eyewear for health care workers caring for patients with suspected or confirmed respiratory tract infections. No relevant literature or evidence-based guidelines were identified; however, articles of potential interest are provided in the appendix. Link to Report Protective Eyewear for […]