Synopsis for the Resumption of Colorectal and Cervical Cancer Screening during the Covid-19 pandemic

Non-urgent cancer treatment procedures were delayed or postponed as a result of the COVID-19 pandemic. There is considerable concern that when screening programs do resume, there may be a backlog of screen-positive patients who may be diagnosed at more advanced stages. CADTH undertook a literature search of scientific evidence, clinical guidelines, recommendations, national standards, and […]

Synopsis of Reference Search Results for Topics in Long-Term Care

The COVID-19 pandemic has been challenging for those living and working in long-term care (LTC) facilities. There has been uncertainty related to managing visitors to LTC, the psychological and social impact of isolation for LTC residents, and how best to support LTC staff during this pandemic. To help support health care decision-makers facing these issues, […]

Systemic Corticosteroids for the Management of COVID-19: A Review of Clinical Effectiveness

There are currently multiple management strategies for COVID-19, including the use of corticosteroids. Preliminary results have found that corticosteroids may lower mortality among severe and critical COVID-19 cases and is recommended for use by those on respiratory support. CADTH has conducted a review to summarize the current clinical evidence on systemic corticosteroids for the management […]

Rapid Point-of-Care Antigen Testing for SARS-CoV-2 Infection

This newsletter explores recent developments in testing for COVID-19. Testing for COVID-19 infection is important to stopping spread of the virus. There is also a need for tests that can quickly provide results. Evidence related to rapid point-of-care antigen testing — such as current practice, availability in Canada, cost, and safety — are summarized in […]

Temperature, Humidity, and COVID-19: Evidence

These citations related to weather and COVID-19 infection are intended to provide a preliminary quick start to enable more comprehensive searching, or to help frame questions or issues.If you would like to know more, please contact CADTH by email or our requests page. Link to Report Temperature, Humidity, and COVID-19: Evidence  

Remdesivir Implementation Panel

Remdesivir (Veklury) is authorized by Health Canada to treat patients with severe COVID-19 symptoms who have pneumonia and need extra oxygen to help them breathe. The drug is administered intravenously and is only to be used in health care facilities where patients can be closely monitored. CADTH recently convened an implementation panel of clinical specialists […]

Ventilation and Perfusion Imaging for the Diagnosis of Pulmonary Embolisms During the COVID-19 Pandemic: A Review of Safety and Guidelines

This Rapid Response review looked for clinical evidence and evidence-based guidelines on ventilation-perfusion imaging for diagnosing pulmonary embolism during the COVID-19 pandemic. Because the procedure often induces coughing in patients, there are concerns about its potential role in transmitting COVID-19 infection from patients to health care providers. However, no relevant evidence or evidence-based guidelines were […]